CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.80 | Glycosidases |
Domain Context
CATH Clusters
| Superfamily | Glycosidases |
| Functional Family | Beta-glucosidase 11 |
Enzyme Information
| 2.4.1.219 |
Vomilenine glucosyltransferase.
based on mapping to UniProt Q9SPP9
UDP-glucose + vomilenine = UDP + raucaffricine.
-!- The indole alkaloid raucaffricine accumulates during the culture of Rauvolfia cell suspensions.
|
| 3.2.1.125 |
Raucaffricine beta-glucosidase.
based on mapping to UniProt Q9SPP9
Raucaffricine + H(2)O = D-glucose + vomilenine.
-!- Highly specific; some other ajmalan glucoside alkaloids are hydrolyzed, more slowly.
|
UniProtKB Entries (1)
| Q9SPP9 |
RG1_RAUSE
Rauvolfia serpentina
Raucaffricine-O-beta-D-glucosidase
|
PDB Structure
| PDB | 3U5U |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structures of alkaloid biosynthetic glucosidases decode substrate specificity.
Acs Chem.Biol.
|
