CATH Domain 3to7A01

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.60	Wheat Germ Agglutinin (Isolectin 2); domain 1
	3.30.60.60	N-acetyl transferase-like

Superfamily	N-acetyl transferase-like
Functional Family

2.3.1.48

Histone acetyltransferase.

based on mapping to UniProt Q08649

Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.

-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

ESA1_YEAST

Saccharomyces cerevisiae S288C

Histone acetyltransferase ESA1

PDB	3TO7
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	MYST protein acetyltransferase activity requires active site lysine autoacetylation. Yuan, H., Rossetto, D., Mellert, H., Dang, W., Srinivasan, M., Johnson, J., Hodawadekar, S., Ding, E.C., Speicher, K., Abshiru, N., Perry, R., Wu, J., Yang, C., Zheng, Y.G., Speicher, D.W., Thibault, P., Verreault, A., Johnson, F.B., Berger, S.L., Sternglanz, R., McMahon, S.B., Cote, J., Marmorstein, R. Embo J.