CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.200 | Phosphorylase Kinase; domain 1 |
|
3.30.200.20 | Phosphorylase Kinase; domain 1 |
Domain Context
CATH Clusters
| Superfamily | Phosphorylase Kinase; domain 1 |
| Functional Family |
Enzyme Information
| 2.7.1.95 |
Kanamycin kinase.
based on mapping to UniProt P0A3Y5
ATP + kanamycin = ADP + kanamycin 3'-phosphate.
-!- Also acts on the antibiotics neomycin, paromomycin, neamine, paromamine, vistamycin and gentamicin A. -!- An enzyme from Pseudomonas aeruginosa also acts on butirosin.
|
UniProtKB Entries (1)
| P0A3Y5 |
KKA3_ENTFL
Enterococcus faecalis
Aminoglycoside 3'-phosphotransferase
|
PDB Structure
| PDB | 3TM0 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis of APH(3')-IIIa-mediated resistance to N1-substituted aminoglycoside antibiotics.
Antimicrob.Agents Chemother.
|
