CATH Classification

Domain Context

CATH Clusters

Superfamily SH2 domain
Functional Family Tyrosine-protein phosphatase non-receptor type

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt Q06124
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

Q06124
PTN11_HUMAN
Homo sapiens
Tyrosine-protein phosphatase non-receptor type 11

PDB Structure

PDB 3TKZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain.
Zhang, Y., Zhang, J., Yuan, C., Hard, R.L., Park, I.H., Li, C., Bell, C., Pei, D.
Biochemistry