CATH Domain 3tgqA01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.170	Beta Complex
	2.170.40	HIV Envelope Protein Gp120; Chain G
	2.170.40.20	Human immunodeficiency virus 1, Gp160, envelope glycoprotein

Domain Context

CATH Clusters

Superfamily	Human immunodeficiency virus 1, Gp160, envelope glycoprotein
Functional Family

Enzyme Information

UniProtKB Entries (1)

ENV_HV1Y2

Human immunodeficiency virus type 1 (isolate YU2)

Envelope glycoprotein gp160

PDB Structure

PDB	3TGQ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops. Kwon, Y.D., Finzi, A., Wu, X., Dogo-Isonagie, C., Lee, L.K., Moore, L.R., Schmidt, S.D., Stuckey, J., Yang, Y., Zhou, T., Zhu, J., Vicic, D.A., Debnath, A.K., Shapiro, L., Bewley, C.A., Mascola, J.R., Sodroski, J.G., Kwong, P.D. Proc.Natl.Acad.Sci.USA