CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.1360 | Gyrase A; domain 2 |
|
3.30.1360.120 | Probable tRNA modification gtpase trme; domain 1 |
Domain Context
CATH Clusters
| Superfamily | Probable tRNA modification gtpase trme; domain 1 |
| Functional Family |
Enzyme Information
| 2.1.1.269 |
Dimethylsulfoniopropionate demethylase.
based on mapping to UniProt Q4FP21
S,S-dimethyl-beta-propiothetin + tetrahydrofolate = 3-(methylthio)propanoate + 5-methyltetrahydrofolate.
-!- The enzyme from the marine bacteria Pelagibacter ubique and Ruegeria pomeroyi are specific toward S,S-dimethyl-beta-propiothetin. -!- They do not demethylate glycine-betaine.
|
UniProtKB Entries (1)
| Q4FP21 |
DMDA_PELUB
Candidatus Pelagibacter ubique HTCC1062
Dimethylsulfonioproprionate demethylase DmdA
|
PDB Structure
| PDB | 3TFJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structures of dimethylsulfoniopropionate-dependent demethylase from the marine organism Pelagabacter ubique.
Protein Sci.
|
