CATH Domain 3tcmA03

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.640	Aspartate Aminotransferase; domain 2
	3.40.640.10	Type I PLP-dependent aspartate aminotransferase-like (Major domain)

Domain Context

CATH Clusters

Superfamily	Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family	alanine aminotransferase 2

Enzyme Information

2.6.1.2

Alanine transaminase.

based on mapping to UniProt P52894

L-alanine + 2-oxoglutarate = pyruvate + L-glutamate.

-!- 2-aminobutanoate acts slowly instead of alanine.

UniProtKB Entries (1)

ALA2_HORVU

Hordeum vulgare

Alanine aminotransferase 2

PDB Structure

PDB	3TCM
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The Enzymology of alanine aminotransferase (AlaAT) isoforms from Hordeum vulgare and other organisms, and the HvAlaAT crystal structure. Duff, S.M., Rydel, T.J., McClerren, A.L., Zhang, W., Li, J.Y., Sturman, E.J., Halls, C., Chen, S., Zeng, J., Peng, J., Kretzler, C.N., Evdokimov, A. Arch.Biochem.Biophys.