CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.540 | Fructose-1,6-Bisphosphatase; Chain A, domain 1 |
|
3.30.540.30 |
Domain Context
CATH Clusters
| Superfamily | 3.30.540.30 |
| Functional Family | Dipeptidyl peptidase 3 |
Enzyme Information
| 3.4.14.4 |
Dipeptidyl-peptidase III.
based on mapping to UniProt Q9NY33
Release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity. Also acts on dipeptidyl 2-naphthylamides.
-!- A cytosolic peptidase that is active at neutral pH. -!- It has broad activity on peptides, although it is highly selective for Arg-Arg-2-naphthylamide, at pH 9.2. -!- Active in the hydrolysis of enkephalins. -!- Belongs to peptidase family M49.
|
UniProtKB Entries (1)
| Q9NY33 |
DPP3_HUMAN
Homo sapiens
Dipeptidyl peptidase 3
|
PDB Structure
| PDB | 3T6J |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Entropy-driven binding of opioid peptides induces a large domain motion in human dipeptidyl peptidase III.
Proc.Natl.Acad.Sci.USA
|
