CATH Domain 3t3mB02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.1510	ntegrin, alpha v. Chain A, domain 3

Domain Context

CATH Clusters

Superfamily	ntegrin, alpha v. Chain A, domain 3
Functional Family	Integrin beta

Enzyme Information

UniProtKB Entries (1)

ITA2B_HUMAN

Homo sapiens

Integrin alpha-IIb

PDB Structure

PDB	3T3M
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure-Guided Design of a High-Affinity Platelet Integrin alphaIIbbeta3 Receptor Antagonist That Disrupts Mg2+ Binding to the MIDAS Zhu, J., Choi, W.S., McCoy, J.G., Negri, A., Zhu, J., Naini, S., Li, J., Shen, M., Huang, W., Bougie, D., Rasmussen, M., Aster, R., Thomas, C.J., Filizola, M., Springer, T.A., Coller, B.S. Sci Transl Med