CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.60 | 4-Layer Sandwich | |
3.60.110 | Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase | |
3.60.110.10 | Carbon-nitrogen hydrolase |
Domain Context
CATH Clusters
Superfamily | Carbon-nitrogen hydrolase |
Functional Family | Glutamine-dependent NAD(+) synthetase |
Enzyme Information
6.3.5.1 |
NAD(+) synthase (glutamine-hydrolyzing).
based on mapping to UniProt P9WJJ3
ATP + deamido-NAD(+) + L-glutamine + H(2)O = AMP + diphosphate + NAD(+) + L-glutamate.
-!- NH(3) can act instead of glutamine (cf. EC 6.3.1.5).
|
UniProtKB Entries (1)
P9WJJ3 |
NADE_MYCTU
Mycobacterium tuberculosis H37Rv
Glutamine-dependent NAD(+) synthetase
|
PDB Structure
PDB | 3SYT |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Regulation of the intersubunit ammonia tunnel in Mycobacterium tuberculosis glutamine-dependent NAD+ synthetase.
Biochem.J.
|