CATH Domain 3smqA02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.70	Distorted Sandwich
	2.70.160	Hnrnp arginine n-methyltransferase1
	2.70.160.11	Hnrnp arginine n-methyltransferase1

Domain Context

CATH Clusters

Superfamily	Hnrnp arginine n-methyltransferase1
Functional Family	protein arginine N-methyltransferase 3 isoform X2

Enzyme Information

2.1.1.-

Methyltransferases.

based on mapping to UniProt O60678

UniProtKB Entries (1)

ANM3_HUMAN

Homo sapiens

Protein arginine N-methyltransferase 3

PDB Structure

PDB	3SMQ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	An allosteric inhibitor of protein arginine methyltransferase 3. Siarheyeva, A., Senisterra, G., Allali-Hassani, A., Dong, A., Dobrovetsky, E., Wasney, G.A., Chau, I., Marcellus, R., Hajian, T., Liu, F., Korboukh, I., Smil, D., Bolshan, Y., Min, J., Wu, H., Zeng, H., Loppnau, P., Poda, G., Griffin, C., Aman, A., Brown, P.J., Jin, J., Al-Awar, R., Arrowsmith, C.H., Schapira, M., Vedadi, M. Structure