CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.320 | Lambda Exonuclease; Chain A |
|
3.90.320.10 |
Domain Context
CATH Clusters
| Superfamily | 3.90.320.10 |
| Functional Family |
Enzyme Information
| 3.1.11.3 |
Exodeoxyribonuclease (lambda-induced).
based on mapping to UniProt P03697
Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 5'-phosphates.
-!- Preference for double-stranded DNA. -!- Does not attack single-strand breaks. -!- Similar enzymes: T4, T5 and T7 exonucleases, mammalian DNase IV. -!- Formerly EC 3.1.4.28.
|
UniProtKB Entries (1)
| P03697 |
EXO_LAMBD
Escherichia virus Lambda
Exonuclease
|
PDB Structure
| PDB | 3SM4 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structures of {lambda} exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity.
Proc.Natl.Acad.Sci.USA
|
