CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.220 | Intramolecular trans-sialidase; domain 3 |
|
2.40.220.10 | Intramolecular Trans-sialidase; Domain 3 |
Domain Context
CATH Clusters
| Superfamily | Intramolecular Trans-sialidase; Domain 3 |
| Functional Family |
Enzyme Information
| 4.2.2.15 |
Anhydrosialidase.
based on mapping to UniProt Q27701
Elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate.
-!- Also acts on N-glycolylneuraminate glycosides. -!- Cf. EC 3.2.1.18 and EC 3.2.1.129. -!- Formerly EC 3.2.1.138.
|
UniProtKB Entries (1)
| Q27701 |
NANL_MACDE
Macrobdella decora
Anhydrosialidase
|
PDB Structure
| PDB | 3SLI |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The 1.8 A structures of leech intramolecular trans-sialidase complexes: evidence of its enzymatic mechanism.
J.Mol.Biol.
|
