CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.10 | Arc Repressor Mutant, subunit A |
|
1.10.10.1140 | Glutamine-dependent NAD+ synthetase, C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Glutamine-dependent NAD+ synthetase, C-terminal domain |
| Functional Family | Glutamine-dependent NAD(+) synthetase |
Enzyme Information
| 6.3.5.1 |
NAD(+) synthase (glutamine-hydrolyzing).
based on mapping to UniProt P9WJJ3
ATP + deamido-NAD(+) + L-glutamine + H(2)O = AMP + diphosphate + NAD(+) + L-glutamate.
-!- NH(3) can act instead of glutamine (cf. EC 6.3.1.5).
|
UniProtKB Entries (1)
| P9WJJ3 |
NADE_MYCTU
Mycobacterium tuberculosis H37Rv
Glutamine-dependent NAD(+) synthetase
|
PDB Structure
| PDB | 3SEZ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Regulation of the intersubunit ammonia tunnel in Mycobacterium tuberculosis glutamine-dependent NAD+ synthetase.
Biochem.J.
|
