CATH Domain 3s2vA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.190	D-Maltodextrin-Binding Protein; domain 2
	3.40.190.10	Periplasmic binding protein-like II

Domain Context

CATH Clusters

Superfamily	Periplasmic binding protein-like II
Functional Family	Glutamate receptor ionotropic, kainate 1

Enzyme Information

UniProtKB Entries (1)

GRIK1_RAT

Rattus norvegicus

Glutamate receptor ionotropic, kainate 1

PDB Structure

PDB	3S2V
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Selective kainate receptor (GluK1) ligands structurally based upon 1H-cyclopentapyrimidin-2,4(1H,3H)-dione: synthesis, molecular modeling, and pharmacological and biostructural characterization. Venskutonyte, R., Butini, S., Coccone, S.S., Gemma, S., Brindisi, M., Kumar, V., Guarino, E., Maramai, S., Valenti, S., Amir, A., Valades, E.A., Frydenvang, K., Kastrup, J.S., Novellino, E., Campiani, G., Pickering, D.S. J.Med.Chem.