CATH Domain 3rv2A01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.300	GMP Synthetase; Chain A, domain 3
	3.30.300.10

Domain Context

CATH Clusters

Superfamily	3.30.300.10
Functional Family	S-adenosylmethionine synthase

Enzyme Information

2.5.1.6

Methionine adenosyltransferase.

based on mapping to UniProt B2HP50

ATP + L-methionine + H(2)O = phosphate + diphosphate + S-adenosyl-L- methionine.

-!- Formerly EC 2.4.2.13.

UniProtKB Entries (1)

METK_MYCMM

Mycobacterium marinum M

S-adenosylmethionine synthase

PDB Structure

PDB	3RV2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Increasing the structural coverage of tuberculosis drug targets. Baugh, L., Phan, I., Begley, D.W., Clifton, M.C., Armour, B., Dranow, D.M., Taylor, B.M., Muruthi, M.M., Abendroth, J., Fairman, J.W., Fox, D., Dieterich, S.H., Staker, B.L., Gardberg, A.S., Choi, R., Hewitt, S.N., Napuli, A.J., Myers, J., Barrett, L.K., Zhang, Y., Ferrell, M., Mundt, E., Thompkins, K., Tran, N., Lyons-Abbott, S., Abramov, A., Sekar, A., Serbzhinskiy, D., Lorimer, D., Buchko, G.W., Stacy, R., Stewart, L.J., Edwards, T.E., Van Voorhis, W.C., Myler, P.J. Tuberculosis (Edinb)