CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.630 | Aminopeptidase | |
3.40.630.20 | Peptidase C15, pyroglutamyl peptidase I-like |
Domain Context
CATH Clusters
Superfamily | Peptidase C15, pyroglutamyl peptidase I-like |
Functional Family | Pyrrolidone-carboxylate peptidase |
Enzyme Information
3.4.19.3 |
Pyroglutamyl-peptidase I.
based on mapping to UniProt P46107
Release of an N-terminal pyroglutamyl group from a polypeptide, the second amino acid generally not being Pro.
-!- Removes 5-oxoproline from various penultimate amino acid residues except L-proline. -!- Inhibited by thiol-blocking reagents. -!- Belongs to peptidase family C15. -!- Formerly EC 3.4.11.8.
|
UniProtKB Entries (1)
P46107 |
PCP_BACAM
Bacillus amyloliquefaciens
Pyrrolidone-carboxylate peptidase
|
PDB Structure
PDB | 3RO0 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Terpyridine platinum(II) complexes inhibit cysteine proteases by binding to active-site cysteine.
J.Biomol.Struct.Dyn.
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