CATH Classification

Domain Context

CATH Clusters

Superfamily 2.60.120.200
Functional Family Botulinum neurotoxin type A

Enzyme Information

3.4.24.69
Bontoxilysin.
based on mapping to UniProt P19321
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
-!- Belongs to peptidase family M27.

UniProtKB Entries (1)

P19321
BXD_CBDP
Clostridium botulinum D phage
Botulinum neurotoxin type D

PDB Structure

PDB 3RMX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Novel Ganglioside-mediated Entry of Botulinum Neurotoxin Serotype D into Neurons.
Kroken, A.R., Karalewitz, A.P., Fu, Z., Kim, J.J., Barbieri, J.T.
J.Biol.Chem.
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