CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.1150 | Aspartate Aminotransferase, domain 1 |
|
3.90.1150.10 | Aspartate Aminotransferase, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Aspartate Aminotransferase, domain 1 |
| Functional Family | Histidine decarboxylase |
Enzyme Information
| 4.1.1.28 |
Aromatic-L-amino-acid decarboxylase.
based on mapping to UniProt P20711
(1) L-dopa = dopamine + CO(2). (2) 5-hydroxy-L-tryptophan = 5-hydroxytryptamine + CO(2).
-!- Also acts on other aromatic L-amino acids, including L-tryptophan. -!- Formerly EC 4.1.1.26 and EC 4.1.1.27.
|
UniProtKB Entries (1)
| P20711 |
DDC_HUMAN
Homo sapiens
Aromatic-L-amino-acid decarboxylase
|
PDB Structure
| PDB | 3RBF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases.
Proc.Natl.Acad.Sci.USA
|