×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily Isopropylmalate Dehydrogenase
Functional Family 3-isopropylmalate dehydrogenase

Enzyme Information

1.1.1.85
3-isopropylmalate dehydrogenase.
based on mapping to UniProt P93832
(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO(2) + NADH.

UniProtKB Entries (1)

P93832
LEU32_ARATH
Arabidopsis thaliana
3-isopropylmalate dehydrogenase 2, chloroplastic

PDB Structure

PDB 3R8W
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and functional evolution of isopropylmalate dehydrogenases in the leucine and glucosinolate pathways of Arabidopsis thaliana.
He, Y., Galant, A., Pang, Q., Strul, J.M., Balogun, S.F., Jez, J.M., Chen, S.
J.Biol.Chem.
CATH-Gene3D is a Global Biodata Core Resource Learn more...