CATH Domain 3qrfM01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.340	Rel homology domain (RHD), DNA-binding domain

Domain Context

CATH Clusters

Superfamily	Rel homology domain (RHD), DNA-binding domain
Functional Family	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

Enzyme Information

UniProtKB Entries (1)

FOXP3_HUMAN

Homo sapiens

Forkhead box protein P3

PDB Structure

PDB	3QRF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells. Bandukwala, H.S., Wu, Y., Feuerer, M., Chen, Y., Barboza, B., Ghosh, S., Stroud, J.C., Benoist, C., Mathis, D., Rao, A., Chen, L. Immunity