CATH Domain 3qr0A03

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.20	Alpha-Beta Barrel
	3.20.20	TIM Barrel
	3.20.20.190	Phosphatidylinositol (PI) phosphodiesterase

Domain Context

CATH Clusters

Superfamily	Phosphatidylinositol (PI) phosphodiesterase
Functional Family

Enzyme Information

UniProtKB Entries (1)

F2YQ19_SEPOF

Sepia officinalis

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase

PDB Structure

PDB	3QR0
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	An autoinhibitory helix in the C-terminal region of phospholipase C-beta mediates Galphaq activation. Lyon, A.M., Tesmer, V.M., Dhamsania, V.D., Thal, D.M., Gutierrez, J., Chowdhury, S., Suddala, K.C., Northup, J.K., Tesmer, J.J. Nat.Struct.Mol.Biol.