CATH Domain 3qlyA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.430	Dihydrofolate Reductase, subunit A
	3.40.430.10	Dihydrofolate Reductase, subunit A

Domain Context

CATH Clusters

Superfamily	Dihydrofolate Reductase, subunit A
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q6FPH0_CANGA

[Candida] glabrata CBS 138

Uncharacterized protein

PDB Structure

PDB	3QLY
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structures of Candida albicans Dihydrofolate Reductase Bound to Propargyl-Linked Antifolates Reveal the Flexibility of Active Site Loop Residues Critical for Ligand Potency and Selectivity. Paulsen, J.L., Bendel, S.D., Anderson, A.C. Chem.Biol.Drug Des.