CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family Tyrosine-protein phosphatase non-receptor type 1

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P18031
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P18031
PTN1_HUMAN
Homo sapiens
Tyrosine-protein phosphatase non-receptor type 1

PDB Structure

PDB 3QKQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The molecular details of WPD-loop movement differ in the protein-tyrosine phosphatases YopH and PTP1B.
Brandao, T.A., Johnson, S.J., Hengge, A.C.
Arch.Biochem.Biophys.
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