CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
| Superfamily | Aldolase class I |
| Functional Family |
Enzyme Information
| 5.3.99.10 |
Thiazole tautomerase.
based on mapping to UniProt P25053
2-((2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene)ethyl phosphate = 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate.
-!- The enzyme catalyzes the irreversible aromatization of the thiazole moiety of 2-((2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene)ethyl phosphate.
|
UniProtKB Entries (1)
| P25053 |
TENI_BACSU
Bacillus subtilis subsp. subtilis str. 168
Thiazole tautomerase
|
PDB Structure
| PDB | 3QH2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A Missing Enzyme in Thiamin Thiazole Biosynthesis: Identification of TenI as a Thiazole Tautomerase.
J.Am.Chem.Soc.
|
