CATH Domain 3qg2A01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.430	Dihydrofolate Reductase, subunit A
	3.40.430.10	Dihydrofolate Reductase, subunit A

Domain Context

CATH Clusters

Superfamily	Dihydrofolate Reductase, subunit A
Functional Family	Bifunctional dihydrofolate reductase-thymidylate synthase

Enzyme Information

UniProtKB Entries (1)

D9N170_PLAFA

Plasmodium falciparum

Bifunctional dihydrofolate reductase-thymidylate synthase

PDB Structure

PDB	3QG2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Trypanosomal dihydrofolate reductase reveals natural antifolate resistance Vanichtanankul, J., Taweechai, S., Yuvaniyama, J., Vilaivan, T., Chitnumsub, P., Kamchonwongpaisan, S., Yuthavong, Y. Acs Chem.Biol.