1 keywords

CATH Domain 3qb1A00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.20 Up-down Bundle
Topology 1.20.1250 Growth Hormone; Chain: A;
Homologous Superfamily 1.20.1250.10  

Domain Context

CATH Clusters

Superfamily 1.20.1250.10
Functional Family Interleukin-2

Enzyme Information

UniProtKB Entries (1)

P60568
IL2_HUMAN
Homo sapiens
Interleukin-2

PDB Structure

PDB 3QB1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'
Levin, A.M., Bates, D.L., Ring, A.M., Krieg, C., Lin, J.T., Su, L., Moraga, I., Raeber, M.E., Bowman, G.R., Novick, P., Pande, V.S., Fathman, C.G., Boyman, O., Garcia, K.C.
Nature