CATH Classification

Domain Context

CATH Clusters

Superfamily Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family Histone acetyltransferase

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt Q9H7Z6
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (1)

Q9H7Z6
KAT8_HUMAN
Homo sapiens
Histone acetyltransferase KAT8

PDB Structure

PDB 3QAH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Regulation of the histone acetyltransferase activity of hMOF via autoacetylation of Lys274
Sun, B., Guo, S., Tang, Q., Li, C., Zeng, R., Xiong, Z., Zhong, C., Ding, J.
Cell Res.