CATH Domain 3q8hA00

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.1330	60s Ribosomal Protein L30; Chain: A;
	3.30.1330.50	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

Superfamily	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Functional Family	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

4.6.1.12

2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase.

based on mapping to UniProt Q63T71

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl- D-erythritol 2,4-cyclodiphosphate + CMP.

-!- Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis.

ISPF_BURPS

Burkholderia pseudomallei K96243

2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

PDB	3Q8H
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Cytidine derivatives as IspF inhibitors of Burkolderia pseudomallei. Zhang, Z., Jakkaraju, S., Blain, J., Gogol, K., Zhao, L., Hartley, R.C., Karlsson, C.A., Staker, B.L., Edwards, T.E., Stewart, L.J., Myler, P.J., Clare, M., Begley, D.W., Horn, J.R., Hagen, T.J. Bioorg.Med.Chem.Lett.