CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.750 | Transcription Regulator spoIIAA |
|
3.30.750.220 |
Domain Context
CATH Clusters
| Superfamily | 3.30.750.220 |
| Functional Family |
Enzyme Information
| 2.7.7.6 |
DNA-directed RNA polymerase.
based on mapping to UniProt Q859P9
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized. -!- See also EC 2.7.7.19 and EC 2.7.7.48.
|
UniProtKB Entries (1)
| Q859P9 |
RPOLV_BPN4
Escherichia virus N4
Virion DNA-directed RNA polymerase
|
PDB Structure
| PDB | 3Q0A |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
X-ray crystal structures elucidate the nucleotidyl transfer reaction of transcript initiation using two nucleotides.
Proc.Natl.Acad.Sci.USA
|