CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.10 | Arc Repressor Mutant, subunit A |
|
1.10.10.460 | Ribonuclease hii. Domain 2 |
Domain Context
CATH Clusters
| Superfamily | Ribonuclease hii. Domain 2 |
| Functional Family | Ribonuclease |
Enzyme Information
| 3.1.26.4 |
Ribonuclease H.
based on mapping to UniProt O75792
Endonucleolytic cleavage to 5'-phosphomonoester.
-!- Acts on RNA-DNA hybrids.
|
UniProtKB Entries (1)
| Q8TDP1 |
RNH2C_HUMAN
Homo sapiens
Ribonuclease H2 subunit C
|
PDB Structure
| PDB | 3PUF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The structural and biochemical characterization of human RNase H2 complex reveals the molecular basis for substrate recognition and Aicardi-Goutieres syndrome defects.
J.Biol.Chem.
|