1 keywords

CATH Domain 3pnvA01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.620 HUPs

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family Glutamate--tRNA ligase

Enzyme Information

6.1.1.17
Glutamate--tRNA ligase.
based on mapping to UniProt P9WFV9
ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).

UniProtKB Entries (1)

P9WFV9
SYE_MYCTU
Mycobacterium tuberculosis H37Rv
Glutamate--tRNA ligase

PDB Structure

PDB 3PNV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural analysis of the non-discriminating glutamyl-tRNA synthetase from Mycobacterium tuberculosis suggests minor role of anticodon recognition in tRNA(Gln) discrimination
Laurinavichiute, D., Bruning, M., Shkolnaya, L.A., Bourenkov, G.P., Domanski, G., Konarev, P., Svergun, D., Strizhov, N.I., Kachalova, G.S., Bartunik, H.D.
To be Published