1 keywords

CATH Domain 3pl6A02

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family HLA class II histocompatibility antigen, DR alpha chain

Enzyme Information

UniProtKB Entries (1)

A0A173ADG5
A0A173ADG5_HUMAN
Homo sapiens
HLA class II histocompatibility antigen DQ alpha chain

PDB Structure

PDB 3PL6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC.
Sethi, D.K., Schubert, D.A., Anders, A.K., Heroux, A., Bonsor, D.A., Thomas, C.P., Sundberg, E.J., Pyrdol, J., Wucherpfennig, K.W.
J.Exp.Med.