CATH Classification

Domain Context

CATH Clusters

Superfamily Medium-chain alcohol dehydrogenases, catalytic domain
Functional Family Alcohol dehydrogenase AdhP

Enzyme Information

1.1.1.1
Alcohol dehydrogenase.
based on mapping to UniProt P42328
(1) A primary alcohol + NAD(+) = an aldehyde + NADH. (2) A secondary alcohol + NAD(+) = a ketone + NADH.
-!- Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol. -!- The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.

UniProtKB Entries (1)

P42328
ADH3_GEOSE
Geobacillus stearothermophilus
Alcohol dehydrogenase

PDB Structure

PDB 3PII
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of mutant of ht- Alcohol dehydrogenase
Dong, M., Bahnson, B.J.
To be Published