CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family Triosephosphate isomerase

Enzyme Information

4.2.3.3
Methylglyoxal synthase.
based on mapping to UniProt P36186
Glycerone phosphate = methylglyoxal + phosphate.
-!- Does not act on D-glyceraldehyde 3-phosphate. -!- Formerly EC 4.2.99.11.
5.3.1.1
Triose-phosphate isomerase.
based on mapping to UniProt P36186
D-glyceraldehyde 3-phosphate = glycerone phosphate.

UniProtKB Entries (1)

P36186
TPI1_GIAIN
Giardia intestinalis
Triosephosphate isomerase

PDB Structure

PDB 3PF3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Determining the molecular mechanism of inactivation by chemical modification of triosephosphate isomerase from the human parasite Giardia lamblia: A study for antiparasitic drug design.
Enriquez-Flores, S., Rodriguez-Romero, A., Hernandez-Alcantara, G., Oria-Hernandez, J., Gutierrez-Castrellon, P., Perez-Hernandez, G., Mora-Ide, L., Castillo-Villanueva, A., Garcia-Torres, I., Mendez, S.T., Gomez-Manzo, S., Torres-Arroyo, A., Lopez-Velazquez, G., Reyes-Vivas, H.
Proteins