CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1580 | Nucleoside phosphorylase domain |
Domain Context
CATH Clusters
| Superfamily | Nucleoside phosphorylase domain |
| Functional Family |
Enzyme Information
| 2.4.2.44 |
S-methyl-5'-thioinosine phosphorylase.
based on mapping to UniProt Q9HZK1
S-methyl-5'-thioinosine + phosphate = hypoxanthine + S-methyl-5-thio- alpha-D-ribose 1-phosphate.
-!- No activity with S-methyl-5'-thioadenosine. -!- The catabolism of of 5'-methylthioadenosine in Pseudomonas aeruginosa involves deamination to S-methyl-5'-thioinosine (EC 3.5.4.31) and phosphorolysis to hypoxanthine.
|
UniProtKB Entries (1)
| Q9HZK1 |
MTIP_PSEAE
Pseudomonas aeruginosa PAO1
S-methyl-5'-thioinosine phosphorylase
|
PDB Structure
| PDB | 3OZB |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Methylthioinosine phosphorylase from Pseudomonas aeruginosa. Structure and annotation of a novel enzyme in quorum sensing.
Biochemistry
|