CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family 3-oxoacyl-[acyl-carrier-protein] reductase FabG

Enzyme Information

1.1.1.100
3-oxoacyl-[acyl-carrier-protein] reductase.
based on mapping to UniProt P0A0H9
(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP(+) = 3-oxoacyl-[acyl- carrier-protein] + NADPH.
-!- Exhibits a marked preference for [acyl-carrier-protein] derivatives over CoA derivatives as substrates.

UniProtKB Entries (1)

P0A0H9
FABG_STAAM
Staphylococcus aureus subsp. aureus Mu50
3-oxoacyl-[acyl-carrier-protein] reductase FabG

PDB Structure

PDB 3OSU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the 3-oxoacyl-acyl carrier protein reductase, FabG, from Staphylococcus aureus
Anderson, S.M., Wawrzak, Z., Onopriyenko, O., Edwards, A., Anderson, W.F., Savchenko, A.
To be Published
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