CATH Domain 3os5A01

Level	CATH Code	Description
	2	Mainly Beta
	2.20	Single Sheet
	2.20.110	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
	2.20.110.10	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain

Superfamily	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
Functional Family	Histone-lysine N-methyltransferase SETD7

2.1.1.43

Histone-lysine N-methyltransferase.

based on mapping to UniProt Q8WTS6

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

SETD7_HUMAN

Homo sapiens

Histone-lysine N-methyltransferase SETD7

PDB	3OS5
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability. Esteve, P.O., Chang, Y., Samaranayake, M., Upadhyay, A.K., Horton, J.R., Feehery, G.R., Cheng, X., Pradhan, S. Nat.Struct.Mol.Biol.