CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | Quinoid dihydropteridine reductase |
Enzyme Information
| 1.5.1.34 |
6,7-dihydropteridine reductase.
based on mapping to UniProt Q86A17
A 5,6,7,8-tetrahydropteridine + NAD(P)(+) = a 6,7-dihydropteridine + NAD(P)H.
-!- The substrate is the quinonoid form of dihydropteridine. -!- Not identical with EC 1.5.1.3. -!- Formerly EC 1.6.99.7 and EC 1.6.99.10.
|
UniProtKB Entries (1)
| Q86A17 |
DHPR_DICDI
Dictyostelium discoideum
Dihydropteridine reductase
|
PDB Structure
| PDB | 3ORF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural insights into the dual substrate specificities of mammalian and Dictyostelium dihydropteridine reductases toward two stereoisomers of quinonoid dihydrobiopterin
Febs Lett.
|