CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.2000 | Glycogen Phosphorylase B; |
Domain Context
CATH Clusters
| Superfamily | Glycogen Phosphorylase B; |
| Functional Family | Alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase |
Enzyme Information
| 2.4.1.346 |
Phosphatidyl-myo-inositol dimannoside synthase.
based on mapping to UniProt Q8NNK8
(1) GDP-alpha-D-mannose + 2-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo- inositol = GDP + 2,6-di-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo- inositol. (2) GDP-alpha-D-mannose + 2-O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl- 1D-myo-inositol = GDP + 2-O-(6-O-acyl-alpha-D-mannosyl)-6-O-alpha-D- mannosyl-1-phosphatidyl-1D-myo-inositol.
-!- The enzyme, found in Corynebacteriales, is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIMs). -!- Formerly EC 2.4.1.57.
|
UniProtKB Entries (1)
| Q8NNK8 |
PIMB_CORGL
Corynebacterium glutamicum ATCC 13032
GDP-mannose-dependent monoacylated alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase
|
PDB Structure
| PDB | 3OKC |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Acceptor substrate discrimination in phosphatidyl-myo-inositol mannoside synthesis: structural and mutational analysis of mannosyltransferase Corynebacterium glutamicum PimB'.
J.Biol.Chem.
|