CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.40 | Beta Barrel | |
2.40.70 | Cathepsin D, subunit A; domain 1 | |
2.40.70.10 | Acid Proteases |
Domain Context
CATH Clusters
Superfamily | Acid Proteases |
Functional Family | Renin |
Enzyme Information
3.4.23.15 |
Renin.
based on mapping to UniProt P00797
Cleavage of Leu-|-Xaa bond in angiotensinogen to generate angiotensin I.
-!- Belongs to peptidase family A1. -!- Formerly EC 3.4.4.15 and EC 3.4.99.19.
|
UniProtKB Entries (1)
P00797 |
RENI_HUMAN
Homo sapiens
Renin
|
PDB Structure
PDB | 3OAG |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Design and optimization of new piperidines as renin inhibitors.
Bioorg.Med.Chem.Lett.
|