CATH Classification

Domain Context

CATH Clusters

Superfamily paz domain
Functional Family Piwi-like RNA-mediated gene silencing 2

Enzyme Information

3.1.26.-
Endoribonucleases producing 5'-phosphomonoesters.
based on mapping to UniProt Q8TC59

UniProtKB Entries (1)

Q8TC59
PIWL2_HUMAN
Homo sapiens
Piwi-like protein 2

PDB Structure

PDB 3O7X
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Inaugural Article: Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains.
Tian, Y., Simanshu, D.K., Ma, J.B., Patel, D.J.
Proc.Natl.Acad.Sci.USA