CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.100 | NADP-dependent oxidoreductase domain |
Domain Context
CATH Clusters
| Superfamily | NADP-dependent oxidoreductase domain |
| Functional Family | Aldo-keto reductase family 1 member B1 |
Enzyme Information
| 1.1.1.21 |
Aldehyde reductase.
based on mapping to UniProt Q5RJP0
Alditol + NAD(P)(+) = aldose + NAD(P)H.
-!- Wide specificity. -!- Formerly EC 1.1.1.139.
|
UniProtKB Entries (1)
| Q5RJP0 |
ALD1_RAT
Rattus norvegicus
Aldo-keto reductase family 1 member B7
|
PDB Structure
| PDB | 3O3R |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of rat aldose reductase-like protein AKR1B14 holoenzyme: Probing the role of His269 in coenzyme binding by site-directed mutagenesis
Bioorg.Med.Chem.Lett.
|
