CATH Domain 3o0iA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.565	Heat Shock Protein 90
	3.30.565.10	Histidine kinase-like ATPase, C-terminal domain

Domain Context

CATH Clusters

Superfamily	Histidine kinase-like ATPase, C-terminal domain
Functional Family	Heat shock protein HSP 90-alpha

Enzyme Information

UniProtKB Entries (1)

HS90A_HUMAN

Homo sapiens

Heat shock protein HSP 90-alpha

PDB Structure

PDB	3O0I
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2. Patel, P.D., Yan, P., Seidler, P.M., Patel, H.J., Sun, W., Yang, C., Que, N.S., Taldone, T., Finotti, P., Stephani, R.A., Gewirth, D.T., Chiosis, G. Nat.Chem.Biol.