CATH Domain 3nzmA00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.170	Beta Complex
	2.170.16	Endonuclease - Pi-scei; Chain A, domain 1
	2.170.16.10	Hedgehog/Intein (Hint) domain

Domain Context

CATH Clusters

Superfamily	Hedgehog/Intein (Hint) domain
Functional Family

Enzyme Information

2.7.7.7

DNA-directed DNA polymerase.

based on mapping to UniProt P74750

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P74750

DPO3A_SYNY3

Synechocystis sp. PCC 6803 substr. Kazusa

DNA polymerase III subunit alpha

PDB Structure

PDB	3NZM
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure of catalytically competent intein caught in a redox trap with functional and evolutionary implications. Callahan, B.P., Topilina, N.I., Stanger, M.J., Van Roey, P., Belfort, M. Nat.Struct.Mol.Biol.