CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.287 | Helix Hairpins |
|
1.10.287.1270 |
Domain Context
CATH Clusters
| Superfamily | 1.10.287.1270 |
| Functional Family |
Enzyme Information
| 2.7.11.16 |
[G-protein-coupled receptor] kinase.
based on mapping to UniProt P43250
ATP + [G-protein-coupled receptor] = ADP + [G-protein-coupled receptor] phosphate.
-!- All members of this enzyme subfamily possess a highly conserved binding site for 1-phosphatidylinositol 4,5-bisphosphate. -!- (cf. EC 2.7.11.14 and EC 2.7.11.15).
|
UniProtKB Entries (1)
| P43250 |
GRK6_HUMAN
Homo sapiens
G protein-coupled receptor kinase 6
|
PDB Structure
| PDB | 3NYN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Molecular basis for activation of G protein-coupled receptor kinases.
Embo J.
|
