CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.1220 | Arc Repressor Mutant | |
1.10.1220.110 |
Domain Context
CATH Clusters
Superfamily | 1.10.1220.110 |
Functional Family |
Enzyme Information
1.1.3.17 |
Choline oxidase.
based on mapping to UniProt Q7X2H8
Choline + 2 O(2) + H(2)O = betaine + 2 H(2)O(2).
-!- In many bacteria, plants and animals, the osmoprotectant betaine is synthesized using different enzymes to catalyze the conversion of (1) choline into betaine aldehyde and (2) betaine aldehyde into betaine. -!- In plants, the first reaction is catalyzed by EC 1.14.15.7, whereas in animals and many bacteria, it is catalyzed by either EC 1.1.99.1 or EC 1.1.3.17. -!- The enzyme involved in the second step, EC 1.2.1.8, appears to be the same in those plants, animals and bacteria that use two separate enzymes.
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UniProtKB Entries (1)
Q7X2H8 |
CHOX_ARTGO
Arthrobacter globiformis
Choline oxidase
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PDB Structure
PDB | 3NNE |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural and kinetic studies on the Ser101Ala variant of choline oxidase: Catalysis by compromise.
Arch.Biochem.Biophys.
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