CATH Domain 3njvA02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.1120	Carboxypeptidase-like, regulatory domain

Domain Context

CATH Clusters

Superfamily	Carboxypeptidase-like, regulatory domain
Functional Family	Rhamnogalacturonate lyase A

Enzyme Information

4.2.2.23

Rhamnogalacturonan endolyase.

based on mapping to UniProt Q00019

Endotype eliminative cleavage of L-alpha-rhamnopyranosyl-(1->4)-alpha-D- galactopyranosyluronic acid bonds of rhamnogalacturonan I domains in ramified hairy regions of pectin leaving L-rhamnopyranose at the reducing end and 4-deoxy-4,5-unsaturated D-galactopyranosyluronic acid at the non- reducing end.

-!- The enzyme is part of the degradation system for rhamnogalacturonan I in Bacillus subtilis strain 168 and Aspergillus aculeatus.

UniProtKB Entries (1)

Q00019

RGLA_ASPAC

Aspergillus aculeatus

Rhamnogalacturonate lyase A

PDB Structure

PDB	3NJV
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural and Biochemical Studies Elucidate the Mechanism of Rhamnogalacturonan Lyase from Aspergillus aculeatus. Jensen, M.H., Otten, H., Christensen, U., Borchert, T.V., Christensen, L.L., Larsen, S., Leggio, L.L. J.Mol.Biol.