CATH Domain 3ne4A01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.497	Antithrombin; Chain I, domain 2
	3.30.497.10	Antithrombin, subunit I, domain 2

Domain Context

CATH Clusters

Superfamily	Antithrombin, subunit I, domain 2
Functional Family	Serine protease inhibitor

Enzyme Information

UniProtKB Entries (1)

A1AT_HUMAN

Homo sapiens

Alpha-1-antitrypsin

PDB Structure

PDB	3NE4
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Therapeutic target-site variability in [alpha]1-antitrypsin characterized at high resolution Patschull, A.O., Segu, L., Nyon, M.P., Lomas, D.A., Nobeli, I., Barrett, T.E., Gooptu, B. Acta Crystallogr.,Sect.F