CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Adenylate kinase mitochondrial |
Enzyme Information
| 2.7.4.6 |
Nucleoside-diphosphate kinase.
based on mapping to UniProt P27144
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
-!- Many nucleoside diphosphates can act as acceptors. -!- Many ribo- and deoxyribonucleoside triphosphates can act as donors.
|
| 2.7.4.10 |
Nucleoside-triphosphate--adenylate kinase.
based on mapping to UniProt P27144
NTP + AMP = NDP + ADP.
-!- Many nucleoside triphosphates can act as donors.
|
UniProtKB Entries (1)
| P27144 |
KAD4_HUMAN
Homo sapiens
Adenylate kinase 4, mitochondrial
|
PDB Structure
| PDB | 3NDP |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of human adenylate kinase 4 (L171P) suggests the role of hinge region in protein domain motion
Biochem.Biophys.Res.Commun.
|
